This Central VA SOCRA Chapter Meeting was recorded March 9, 2022. Jeannie Farnsworth, MS, BS, CCRP, MRQA discussed the clinical significance of serious adverse events (SAE) and adverse events (AE) to better understand participant abnormalities and the impact on study outcomes. Ms. Farnsworth explained how to gain a better understanding of how and when abnormalities should be assessed as an AE or SAE. SOCRA