This Central VA SOCRA Chapter Meeting was recorded Wednesday, May 19, 2021. Annette Oeser, Clinical Coordinator, Division of Clinical Pharmacology, Vanderbilt University, MLAS, discussed and presented the ramifications of FDA allowance to charge research participants for investigational products under certain circumstances and recent events in this regulatory area.  Topics covered the definition of “Pay-to-Play” clinical research, specifics of related regulations, and pros and cons of “Pay-to-Play” research. SOCRA.