In "Resolving Urgent Questions," part four of the CRP training series, Michelle Liendo (Director of Clinical Research Operations and Management at Massey), Jill Opalesky (Director of VCU's Human Subjects Research Protection Program), Shelly Orr (Director of Clinical Research Operations for VCU Health), and Juel Secosky (Director of the School of Medicine Clinical Research Office) outline protocols for obtaining immediate guidance. The panel explains how to efficiently resolve time-sensitive issues by following internal chains of command, contacting specific IRB coordinators with HM study numbers, and reaching out to dedicated operational, budgeting, or billing teams.